|
Symbol Name ID |
Ace
angiotensin I converting enzyme MGI:87874 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypercalciuria |
Hematuria |
Urinary mulberry cells |
Decreased level of D-mannose in urine |
Increased level of L-fucose in urine |
Proteinuria |
Lipiduria |
Renal amyloidosis |
Abnormality of the bladder |
Abnormality of the kidney |
IgA deposition in the glomerulus |
Tubulointerstitial nephritis |
Nephrocalcinosis |
Nephrolithiasis |
Polyuria |
Nephritis |
Nephropathy |
Nephrotic syndrome |
Renal insufficiency |
Acute kidney injury |
Chronic kidney disease |
Stage 5 chronic kidney disease |
| Disease(s) Associated with ACE | ||||||||||||||||||||||
| Behcet's disease | ||||||||||||||||||||||
| Fabry disease | ||||||||||||||||||||||
| familial mediterranean fever | ||||||||||||||||||||||
| IgA glomerulonephritis | ||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||
| pre-eclampsia | ||||||||||||||||||||||
| sarcoidosis | ||||||||||||||||||||||
| stomach cancer | ||||||||||||||||||||||
| type 1 diabetes mellitus |
| Mouse Phenotypes | renal/urinary system phenotype |
abnormal kidney arterial blood vessel morphology |
abnormal renal artery morphology |
abnormal kidney vasculature morphology |
kidney medulla cyst |
decreased urine aldosterone level |
increased urine potassium level |
abnormal urine homeostasis |
abnormal urine osmolality |
decreased urine osmolality |
kidney inflammation |
tubulointerstitial nephritis |
abnormal kidney morphology |
abnormal kidney medullary ray morphology |
increased glomerular capsule space |
dilated renal glomerular capsule |
abnormal renal glomerulus morphology |
kidney cortex atrophy |
abnormal kidney corticomedullary boundary morphology |
abnormal kidney medulla morphology |
abnormal kidney papilla morphology |
kidney papillary atrophy |
kidney medulla atrophy |
kidney medulla hypoplasia |
abnormal kidney pelvis morphology |
dilated kidney calyx |
hydronephrosis |
decreased kidney weight |
kidney atrophy |
renal tubule atrophy |
polyuria |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||
| Acetm1Keb/Acetm1Keb | ||||||||||||||||||||||||||||||||
| Acetm1Mcf/Acetm1Mcf | ||||||||||||||||||||||||||||||||
| Acetm1Unc/Acetm1Unc | ||||||||||||||||||||||||||||||||
| Acetm2Keb/Acetm2Keb | ||||||||||||||||||||||||||||||||
| Acetm2Unc/Acetm2Unc | ||||||||||||||||||||||||||||||||
| Acetm3Keb/Acetm3Keb | * | |||||||||||||||||||||||||||||||
| Acetm4Keb/Acetm4Keb | ||||||||||||||||||||||||||||||||
| Acetm8.1Keb/Acetm8.1Keb | * | |||||||||||||||||||||||||||||||
| Acetm8Keb/Acetm8Keb | ||||||||||||||||||||||||||||||||
| Acetm9Keb/Acetm9Keb | ||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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